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Baicheng HUANG, Kegong TIAN
Frontiers of Agricultural Science and Engineering 2020, Volume 7, Issue 2, Pages 218-226 doi: 10.15302/J-FASE-2020324
Keywords: bat coronavirus evolution host receptor spike protein transmission
Ali A. Rabaan, Ali M. Bazzi, Shamsah H. Al-Ahmed, Jaffar A. Al-Tawfiq
Frontiers of Medicine 2017, Volume 11, Issue 3, Pages 365-377 doi: 10.1007/s11684-017-0521-z
Keywords: MERS-CoV Saudi Arabia spike protein transmission evolution vaccine
Molecular Characteristics, Functions, and Related Pathogenicity of MERS-CoV Proteins Review
Yan-Hua Li, Chen-Yu Hu, Nan-Ping Wu, Hang-Ping Yao, Lan-Juan Li
Engineering 2019, Volume 5, Issue 5, Pages 940-947 doi: 10.1016/j.eng.2018.11.035
Middle East respiratory syndrome (MERS) is a viral respiratory disease caused by a de novo coronavirus—Middle East respiratory syndrome coronavirus (MERS-CoV)—that is associated with high mortality. However, the mechanism by which MERS-CoV infects humans remains unclear. To date, there is no effective vaccine or antibody for human immunity and treatment, other than the safety and tolerability of the fully human polyclonal Immunoglobulin G (IgG) antibody (SAB-301) as a putative therapeutic agent specific for MERS. Although rapid diagnostic and public health measures are currently being implemented, new cases of MERS-CoV infection are still being reported. Therefore, various effective measures should be taken to prevent the serious impact of similar epidemics in the future. Further investigation of the epidemiology and pathogenesis of the virus, as well as the development of effective therapeutic and prophylactic anti-MERS-CoV infections, is necessary. For this purpose, detailed information on MERS-CoV proteins is needed. In this review, we describe the major structural and nonstructural proteins of MERS-CoV and summarize different potential strategies for limiting the outbreak of MERS-CoV. The combination
of computational biology and virology can accelerate the advanced design and development of effective peptide therapeutics against MERS-CoV. In summary, this review provides important information about the progress of the elimination of MERS, from prevention to treatment.
Keywords: MERS-CoV Spike protein Structural protein Accessory protein Nonstructural protein
Zeyu Sun, Keyi Ren, Xing Zhang, Jinghua Chen, Zhengyi Jiang, Jing Jiang, Feiyang Ji, Xiaoxi Ouyang, Lanjuan Li
Engineering 2021, Volume 7, Issue 10, Pages 1441-1451 doi: 10.1016/j.eng.2020.07.014
Keywords: N-glycosylation COVID-19 Spike protein hACE2 Structure
Systems understanding of plant–pathogen interactions through genome-wide protein–protein interaction
Hong LI,Ziding ZHANG
Frontiers of Agricultural Science and Engineering 2016, Volume 3, Issue 2, Pages 102-112 doi: 10.15302/J-FASE-2016100
Keywords: plant–pathogen interactions systems biology omics plant immunity protein–protein interaction network
The role of protein kinase C epsilon in neural signal transduction and neurogenic diseases
Yuan CHEN, Qi TIAN
Frontiers of Medicine 2011, Volume 5, Issue 1, Pages 70-76 doi: 10.1007/s11684-011-0119-9
Protein kinase C epsilon (PKC ?) is one of major isoforms in novel PKC family.
Keywords: protein kinase C ? signal transduction neurogenic disease
Wheat gluten protein and its impacts on wheat processing quality
Wujun MA, Zitong YU, Maoyun SHE, Yun ZHAO, Shahidul ISLAM
Frontiers of Agricultural Science and Engineering 2019, Volume 6, Issue 3, Pages 279-287 doi: 10.15302/J-FASE-2019267
Keywords: wheat gluten consensus motifs disulfide bonds SDS-unextractable polymeric protein glutenins gliadins processing quality storage protein
Frontiers of Chemical Science and Engineering 2023, Volume 17, Issue 8, Pages 1131-1139 doi: 10.1007/s11705-023-2321-0
Keywords: biomass riboflavin sodium phosphate silk protein multifunctional modification flame retardant
Antithrombin deficiency and decreased protein C activity in a young man with venous thromboembolism:
Dong Wang, Min Tian, Guanglin Cui, Dao Wen Wang
Frontiers of Medicine 2018, Volume 12, Issue 3, Pages 319-323 doi: 10.1007/s11684-017-0553-4
Antithrombin and protein C are two crucial members in the anticoagulant system and play importantCoagulation tests revealed that the patient presented type I antithrombin deficiency combined with decreased proteinThis study demonstrates that the combination of antithrombin deficiency and decreased protein C activity
Keywords: antithrombin deficiency protein C activity mutation variant venous thromboembolism anticoagulants
Jiangtao YAN, Rutai HUI, Daowen WANG
Frontiers of Medicine 2009, Volume 3, Issue 1, Pages 30-35 doi: 10.1007/s11684-009-0005-x
Keywords: C-reactive protein inflammation stroke
Frontiers of Medicine 2022, Volume 16, Issue 6, Pages 919-931 doi: 10.1007/s11684-021-0918-6
Keywords: preeclampsia recombinant protein diannexin microparticle NLRP3 inflammasome phosphatidylserin
Investigation of hydrolysis conditions and properties on protein hydrolysates from flatfish skin
Hua ZHANG, Hongji ZHU, Shipeng WANG, Weihua WANG
Frontiers of Chemical Science and Engineering 2013, Volume 7, Issue 3, Pages 303-311 doi: 10.1007/s11705-013-1341-6
Keywords: flatfish skin protein hydrolysates metal chelating activity reducing power
Liang ZHUANG, Shiying YU, Xiaoyuan HUANG, Yang CAO, Huihua XIONG
Frontiers of Medicine 2009, Volume 3, Issue 1, Pages 26-29 doi: 10.1007/s11684-009-0008-7
Keywords: Ku80 DNA-PK(cs)-binding protein human ataxia telangiectasia mutated protein tumor cell lines radiosensitivity
Protein phosphatase 2A, a key player in Alzheimer’s disease
Rong LIU, Qing TIAN
Frontiers of Medicine 2009, Volume 3, Issue 1, Pages 8-12 doi: 10.1007/s11684-009-0017-6
Keywords: protein phosphatase 2A Alzheimer’s disease holoenzyme composition protein phosphatase 2A inhibitors Leu309
Molecular mechanisms of leukemia-associated protein degradation
Ying-Li WU, Guo-Qiang CHEN, Hu-Chen ZHOU,
Frontiers of Medicine 2010, Volume 4, Issue 4, Pages 363-370 doi: 10.1007/s11684-010-0210-7
Keywords: protein degradation leukemia chemical biology transcription factors oncoprotein
Title Author Date Type Operation
Interspecies transmission and evolution of the emerging coronaviruses: perspectives from bat physiology and protein
Baicheng HUANG, Kegong TIAN
Journal Article
Molecular aspects of MERS-CoV
Ali A. Rabaan, Ali M. Bazzi, Shamsah H. Al-Ahmed, Jaffar A. Al-Tawfiq
Journal Article
Molecular Characteristics, Functions, and Related Pathogenicity of MERS-CoV Proteins
Yan-Hua Li, Chen-Yu Hu, Nan-Ping Wu, Hang-Ping Yao, Lan-Juan Li
Journal Article
Mass Spectrometry Analysis of Newly Emerging Coronavirus HCoV-19 Spike Protein and Human ACE2 Reveals
Zeyu Sun, Keyi Ren, Xing Zhang, Jinghua Chen, Zhengyi Jiang, Jing Jiang, Feiyang Ji, Xiaoxi Ouyang, Lanjuan Li
Journal Article
Systems understanding of plant–pathogen interactions through genome-wide protein–protein interaction
Hong LI,Ziding ZHANG
Journal Article
The role of protein kinase C epsilon in neural signal transduction and neurogenic diseases
Yuan CHEN, Qi TIAN
Journal Article
Wheat gluten protein and its impacts on wheat processing quality
Wujun MA, Zitong YU, Maoyun SHE, Yun ZHAO, Shahidul ISLAM
Journal Article
Construction of sustainable, colored and multifunctional protein silk fabric using biomass riboflavin
Journal Article
Antithrombin deficiency and decreased protein C activity in a young man with venous thromboembolism:
Dong Wang, Min Tian, Guanglin Cui, Dao Wen Wang
Journal Article
Elevated C-reactive protein levels predict worsening prognosis in Chinese patients with first-onset stroke
Jiangtao YAN, Rutai HUI, Daowen WANG
Journal Article
Recombinant protein diannexin prevents preeclampsia-like symptoms in a pregnant mouse model via reducing
Journal Article
Investigation of hydrolysis conditions and properties on protein hydrolysates from flatfish skin
Hua ZHANG, Hongji ZHU, Shipeng WANG, Weihua WANG
Journal Article
Correlativity study between expression of DNA double-strand break repair protein and radiosensitivity
Liang ZHUANG, Shiying YU, Xiaoyuan HUANG, Yang CAO, Huihua XIONG
Journal Article